Following successful residencies at The Princess Alexandra Hospital and registrar and senior registrar positions at The South Brisbane Haematology/Oncology Unit and The Queensland Radium Institute at Royal Brisbane Hospital, Dr Grimes completed a clinical fellowship at the Roswell Park Cancer Institute New York in 1993 and 1994 specialising in bone marrow transplantation and medical oncology.
Dr Grimes continues to participate in clinical research and serves on several national advisory boards, he has, since its inception been convener for The South East Queensland Oncology group. His clinical experience covers a broad range of solid tumour malignancies, with a clinical interest in breast cancer, gastrointestinal cancer, genitourinary cancer, colorectal cancer, prostate cancer, pancreatic cancer, gynaecological cancer and thoracic cancers.